Weight Loss

10 Health Conditions That Can Cause Unexplained Weight Loss

3. Hyperthyroidism

Sudden unexplained weight loss with no change or a decrease in appetite can be an indication of thyroid problem, particularly hyperthyroidism.

Hyperthyroidism is an abnormal increase in the activity of the thyroid gland causing excess production of thyroid hormone.

The high amounts of these thyroid hormones (Thyroxine and Triiodothyronine) circulating in the blood can cause an exponential increase in metabolic rate, leading to increased burning of energy in the body.

Apart from that, hyperthyroidism also speeds up your heart rate and causes excess sweating, panic attacks, mood swings, hot flushes, muscle weakness, and fatigue.

4. Tuberculosis


Unexplained weight loss can be a major warning sign of tuberculosis (TB). One of the first symptoms of any serious infection is unexpected weight loss due to loss of appetite (2).

Tuberculosis is a contagious disease caused by Mycobacterium tuberculosis.

It affects mostly the lungs but can spread to other parts of your body including the bones, lymph nodes, reproductive system, digestive system, and nervous system.

Apart from unexplained weight loss, other symptoms of tuberculosis include a persistent cough that lasts more than three weeks, fever, night sweat, extreme fatigue, and other symptoms depending on the severity and the organ affected by the infection.

5. Parasite Infestation

A parasitic infestation in your stomach could be another reason for unexplained weight loss. Several types of parasites live and feed off your body, and some of them depend on the food you eat for survival.

Some of them include tapeworms, pinworms, and hookworms which enter your body either through the skin or by ingestion.

One of the early sign of parasitic infestation is an increase in appetite because the parasites consume a good amount of the food you consume. This makes you get hungry more frequently than usual.

However, a study published in the PLoS journal reports that weight loss following a worm infestation could be the body’s way of warding off the worms (3).

In addition to increased appetite and weight loss, other warning signs of parasite infestation include diarrhea, abdominal pain, anal itching, lack of energy and nutritional deficiencies.

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